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Artesunate 50 mg Tablet

Artesunate 50 mg Tablet
Artesunate 50 mg Tablet
Product Code : 10
Product Description

Artesunate Tablet, Artesunate 50 mg Tablet

 

Details of Artesunate 50 mg Tablet :-

1. Name and Chemical Structure :-

  • Generic Name: Artesunate
  • Chemical Name: Dihydroartemisinine-10-a-Swccinate
  • Molecular Formula: C19H28O8 = 383.43

2. Description :-

It is a white crystalline powder that is odorless and almost insipid.

3. Pharmacological Effects :-

Artesunate has an outstanding anti-malarial activity on the nonsexual forms of malaria organisms with advanced, fast efficiency to bring about rapid power of an intense attack. It has benefits of no cross action to Chloroquine.

4. Absorption, Distribution and Excretion :-

The density of Artesunate in plasma decreases quickly after managed intravenously. The half-life time of plasma is about 30 minutes. It administers widely throughout the body and with advanced concentration in liver, intestines and kidneys. Only a little quantity of the medicine passes in stools and urine. It is primarily obviated by metabolic bio-transformation.

5. Indications of Artesunate Tablet :-

Artesunate 50 mg Tablet is formulated for killing the erythrocyte stage of cytoplasm asexual variety. It is efficacious to malaria grounded by antimalarial immune stain of plasmodium falciparum. Malarine can speedily and dependably control the chronic affliction of malaria. It is appropriate to salvage the sufferer with pestilent malaria and P. vivax malaria and P. falciparum malaria. The Artesunate Injection is used for the treatment of chronic malaria contagions and the patients with cerebral protozoal infection.

6. Administration and Dosage :-

  • Dosages for the treatment: Oral 50 mg, two times in a day for 5 days consecutively. Twofold doses on the first day.
  • Dosages for the prevention of Malaria: By mouth, 100mg one time in a week, from one week preceding to the entering of malarial orbits, to four weeks after the departure from the area.
  • Doses for Children: 2mg/kg in the morning time and evening on the first day; 1mg/kg in the morning and evening from second to fifth day.

7. Harmful Reactions :-

No harmful reactions were determined with recommended dosages up to now. Immanent reticulocytopenia may fall out in the overdosing of Artesunate Injection, if more than 3.75 mg/kg is given.

8. Notes :-

Embryo-toxic effects were detected in some animal surveys. The usage of Artesunate should be executed with care in pregnant women during the initial three months of pregnancy.

9. Storage :-

Store the Artesunate 50 mg Tablet at room temperature, 15-30°C (59-86°F) and store in a lightless area.

10. Packing :-

Artesunate Tablet: 50 mg x12’s/box (UD)


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