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Generic Name : PaclitaxelIngection
Manufacturer : RND
Bd-TAXEL injectionis used to treat advanced cancer of the ovaries, breast, non-small cell lungcancer, and Kaposi sarcoma. Kaposi sarcoma is a cancer of the skin and mucous membranesthat is commonly found in patients with acquired immunodeficiency syndrome(AIDS).
Bd-TAXEL belongs to the group of medicines calledantineoplastics. It interferes with the growth of cancer cells, which areeventually destroyed. Since the growth of normal body cells may also beaffected, other unwanted effects will also occur. Some of these may be seriousand must be reported to your doctor. Other effects may not be serious but maycause concern. Some effects may not occur until months or years after themedicine is used.
Use Bd-TAXEL as directed by your doctor. Check the label on themedicine for exact dosing instructions.
Bd-TAXELis used alone or in combination with other chemotherapeutic agents in thetreatment of ovarian cancer, breast cancer, advanced non-small cell lungcancer, cancer of pancreas, and AIDS related Kaposi s sarcoma (a type of cancerthat develops from the cells that line lymph or blood vessels). This can alsobe used to treat patients who may be non-responsive to anthracycline basedtherapies.
Hematologic: Bone marrow suppression was the major dose-limiting toxicity ofBd-TAXEL. Neutropenia, the most important hematologic toxicity, was dose- andschedule-dependent and was generally rapidly reversible. Among patients treatedin phase 3 second-line ovarian study with a 3-hr infusion, neutrophil countsdeclined <500 cells/mm3 in 14% of patients treated with adose of 135 mg/m2 compared to 27% at a dose of 175 mg/m2 (p=0.05).