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Generic Name : Paclitaxel Injection
Manufacturer : RND
Bd-TAXEL injection is used to treat advanced cancer of the ovaries, breast, non-small cell lung cancer, and Kaposi sarcoma. Kaposi sarcoma is a cancer of the skin and mucous membranes that is commonly found in patients with acquired immunodeficiency syndrome(AIDS).
Bd-TAXEL belongs to the group of medicines called antineoplastics. It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also beaffected, other unwanted effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur until months or years after the medicine is used.
Use Bd-TAXEL as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Bd-TAXELis used alone or in combination with other chemotherapeutic agents in the treatment of ovarian cancer, breast cancer, advanced non-small cell lung cancer, cancer of pancreas, and AIDS related Kaposi s sarcoma (a type of cancer that develops from the cells that line lymph or blood vessels). This can also be used to treat patients who may be non-responsive to anthracycline based therapies.
Hematologic: Bone marrow suppression was the major dose-limiting toxicity ofBd-TAXEL. Neutropenia, the most important hematologic toxicity, was dose- and schedule-dependent and was generally rapidly reversible. Among patients treatedin phase 3 second-line ovarian study with a 3-hr infusion, neutrophil counts declined <500 cells/mm3 in 14% of patients treated with a dose of 135 mg/m2 compared to 27% at a dose of 175 mg/m2 (p=0.05).