Product Description

Product Name :Adben 100 mg

Generic Name : Bendamustine Injection

Manufacturer : Adley

What Bendamustine Is Used For:

• It is used for treatment of chronic lymphocytic leukemia (CLL).
• It is used for the treatment of patients with indolent B-cell non-Hodgkin's lymphoma.

How Bendamustine Is Given:

As an injection into the vein (intravenous, IV).

There is no pill form of Bendamustine.

Bendamustine Side Effects:

Important things to remember about the side effects of Bendamustine:

Most people will not experience all ofthe Bendamustine side effects listed.

Bendamustine side effects are often predictable in terms of their onset, duration, and severity.

Bendamustine side effects are almost always reversible and will go away after therapy is complete.

Bendamustine side effects may be quite manageable. There are many options to minimize or prevent the side effects of Bendamustine .

Bendamustine Precautions:

Before starting Bendamustine treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). While taking Bendamustine do not take aspirin or products containing aspirin unless your doctor specifically permits this.

While taking Bendamustine , do not receive any kind of immunization or vaccination without your doctor's approval.

Inform your health care professional if you are pregnant or maybe pregnant prior to starting Bendamustine. Pregnancy category D (Bendamustine may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).

How Bendamustine Works:

Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. "Normal"cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition.  Cancerous cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis(division).

The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division.  Usually, the drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division.  If the cells are unable to divide, they die.  The faster the cells are dividing, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink.  They also induce cell suicide (self-death or apoptosis).