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Product name : Lumigan
Generic Name : Bimatoprost
Manufacturer : Allergan
Lumigan general information
What is Lumigan used for?
Lumigan eye drops 0.03% (also known as Latisse in the US) are used to lower pressure within the eye, known as intraocular pressure (IOP) in the treatment of glaucoma, which is raised IOP caused by a build up of fluid (aqueous humour) in the eye. The increased IOP can cause damage to the optic nerve fibres that lead out of the back of the eye to the brain and may lead gradual loss of sight, starting with peripheral vision and eventually to total blindness in that eye. Lumigan eye drops increases the drainage of aqueous fluid out of the eye which decreases IOP and prevents loss of sight. Lumigan eye drops are also used to treat ocular hypertension (increased IOC without occular nerve damage) to lower IOC. Lumigan eye drops 0.03% are also used to treat hypotrichosis, which is when eyelash growth is abnormal or not sufficient to give you adequate or enough eyelashes to allow you to grow longer, thicker and darker eyelashes.
How does Lumigan work?
Lumigan eye drops contain bimatoprost 0.03%, a synthetic analogue (mimic) of the naturally occurring prostamide, which is a prostaglandin-like chemical that has distinct and specific actions in various tissues of the body, including potent ocular hypotensive (pressure reducing) activity. The build up of pressure in the eye that is seen in glaucoma is caused by a blockage in the draining system for the eye fluid called aqueous humour, which is produced continually to maintain normal eye pressure. Bimatoprost in Lumigan eye drops binds to the same receptors in the eye as prostamide and increases the flow of aqueous humour out of the eye through the spongy tissue called the trabecular network, which is the conventional drainage route for the aqueous, by reducing the tonographic (pressure-sensitive) resistance to outflow of aqueous humour. As the flow of fluid into and out of the eye becomes balanced again, the pressure in the eye is lowered and this reduces the risk of damage to the optic nerve and loss of sight that can happen if glaucoma is left untreated.
What does Lumigan contain?
Lumigan eye drops contain the active ingredient bimatoprost 300mcg/ml (0.03%), a synthetic analogue of prostamide used to lower intraocular pressure (IOP) in glaucoma. They also contain sodium phosphate dibasic, sodium chloride, citric acid monohydrate purified water and the preservative benzalkonium chloride; sodium hydroxide and/or hydrochloric acid may be added to adjust PH. (An applicator is not supplied but a very fine eyeliner brush is suitable)